Join Ash accompanied by his partner Pikachu, as he travels through many regions, meets new friends and faces new challenges on his quest to become a Pokémon Master.
Back in Pallet Town, Ash finds Gary, already there, waiting to partake in the Pokémon League. Always having a bitter rivalry with Gary, Professor Oak tells them both the meaning of Pokémon. Meanwhile, Team Rocket is trying to get inside the lab to steal the Pokémon.
Ash goes to Seafoam Island to help Professor Oak to discover the mystery of how Slowpoke evolves into Slowbro. There, Professor Westwood V is also trying to solve the mystery. Jessie captures Shellder, and tries to rush a Slowpoke's evolution, forcing Psyduck to stall the evolution.
Ash and the gang take some time off to go surfing. While surfing, however, Ash passes out, but is thankfully rescued by a surfer named Victor and his blue-eyed Pikachu, Puka. Victor then reveals his plans to surf a tsunami called Humungadunga and become a surfing legend.
Ash goes to a flower garden to get some fertilizer for his mother, but Bulbasaur sniffs the flowers and becomes paralyzed.
When the gang discovers there is a movie with an all-Pokémon cast being made nearby, Ash and his friends put their Pokémon in for an audition. Misty's Psyduck gets the main role while the others get minor roles.
Ash and his friends go to Hollywood (although only a small nearby town) to see the premiere of the movie their Pokémon were cast in. Team Rocket follows them to find out that Meowth has history in this town; It is here where he was a member of a gang of street Meowths led by the Persian. He learned to speak and walk upright to win the heart of a female Meowth who was abandoned by her owner. Upon returning, he challenges Persian who was once his mentor for the female Meowth he thought he lost years before.